The Glyco-What?

The glycocalyx, which is the sugar-rich outer coating on all eukaryotic cell membranes, mediates cell-cell, cell-extracellular matrix (ECM) interactions, and senses other extracellular cues physiologically. Glycocalyx biopolymers (glycopolymers) are
ubiquitous in the body and dysregulated in various pathological states. We are interested in how cell-surface glycans contributes to disease progression, cellular communication, and tissue remodeling.

Mission

We aim to generate creative approaches in understanding mechanisms in disease through the lens of the cell-surface glycocalyx with rigorous and meaningful science, collaborations, and integrity as well as being respectful of those who are doing the science, those who we impact, and the identities in between and beyond.

Vision

Our group aims to harness the biophysical and biochemical nature of the glycocalyx in understanding disease progression and developing future therapeutic targets and diagnostic markers in disease.